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Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 90: Zoster pain and the pain of using PPIs with clopidogrel

In episode 90, Mike and James solicit the mainly brilliant, but always delightful help of Mike Kolber and Tina Korownyk. We talk about what to do for the chronic pain that can be associated with Herpes zoster and we have a quick look at the old and new data surrounding the area of PPIs and platelet inhibitors. Mike and James cap off the podcast by deciding that Mike and Tina do a way better job than they do so they sell the podcast to the new duo for a brand name PPI and a generic cup of coffee.

Show notes

1) Chronic pain – dual therapy gabapentin plus nortriptyline

Lancet 2009;374:1252-61

2) Clopidogrel and PPIs

JAMA 2009;301:937-44

CMAJ 2009;180:713-8

Lancet 2009; 374: 989–97

Circulation 2009;120:2322-9

Circulation 2009;120;2310-2

COGENT

3) Duration of clopidogrel

N Engl J Med 2010;362:1374-82

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