In episode 516, James and Mike invite Nicolas Dugré to the podcast yet again, and this time we talk about the evidence around the latest long-acting implantable reversible contraception. As always, we talk about the efficacy, the harm and all the rest of the issues around the use of these forms of contraception.

Show Notes

Tools For Practice
The LARC (long-acting reversible contraception) Song: Is the etonogestrel implant a hit?

Check out the Pharmascope Podcast – The French “version” of the BS Medicine Podcast

In episode 515, James and Mike invite Allison Paige to the podcast for the first time. Alli takes us through all the evidence around a combination product (naltrexone/bupropion) for weight loss. We talk about all the numbers we have for benefit, harm and cost and we put this agent into the context of the other medications we use for weight loss.

Show Notes

Tools For Practice

Weight to Go: Naltrexone/bupropion for weight loss

In episode 514, James and Mike invite Betsy Thomas to the podcast for the first time. We look at a very common condition that many of us have at some point in our lives – allergic rhinosinusitis. We go over the best available evidence for the oral antihistamines and try to figure out which one is the “best”. In addition, we look at the evidence for intranasal corticosteroids and they are likely more effective than oral antihistamines.

Show Notes

Tools For Practice

Antihistamines for allergic rhinosinusitis: ‘Achoo’sing the right treatment

In episode 513, James and Mike invite Emelie Braschi to the podcast for the first time. We go over the best available evidence around the treatment of BPH and focus on the combination therapy of alpha-blockers and 5-alpha reductase and find as for many things there is an improvement in symptoms but also an increase in side effects.

Show Notes

Tools For Practice

To Pee or Not to Pee: Combination agents for benign prostatic hypertrophy

In episode 512, James and Mike finish going over the best available evidence around drinking alcohol. We look at what evidence says about the “red-wine” theory and the French Paradox. We also look at the evidence around alcohol and surrogate markers, and atrial fibrillation. We also examine the effect of social drinking on emotion and alcohol-induced cirrhosis.

Show Notes

Check out the book “The Nutrition Proposition” for all the references discussed. The book is available on Amazon as a paperback and a Kindle Edition

Website

Amazon link

In episode 511, James and Mike go on a binge and dissect the best available evidence around alcohol – more specifically 0-3 drinks a day. We look at what is a “drink” and then dive into one of the largest reviews of alcohol ever done. We explore what that evidence suggests about the harms and the benefits, and as always we discuss what the numbers really say.

Show Notes

Check out the book “The Nutrition Proposition” for all the references discussed. The book is available on Amazon as a paperback and a Kindle Edition

1. Website
   nutritionproposition.com
2. Amazon link

In episode 510, Mike and James talk about a trial that looks at what happens when you discontinue antidepressants in primary care. We see there is about a 15% absolute difference in the chance of relapse – and we put all this into context because this is a PREMIUM podcast. We also discuss what happens…

In episode 509, James, Mike and Tina finish talking about our new clinical practice guideline on chronic pain. We focus on the top questions we all have in chronic pain and also discuss the best available evidence for the many different medications we use for chronic pain.

Show Notes

1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
2. Guideline summary
3. Patient Handout
4. PEER pain calculator
5. Tame the Beast

In episode 508, James and Mike ask Tina to come in and talk about our new clinical practice guideline on chronic pain. We focus on the best available evidence which shows that physical activity is key (except for neuropathic pain). We also go over the role for psychological interventions and the problem with opioids.

Show Notes

1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
2. Guideline summary
3. Patient Handout
4. PEER pain calculator

In episode 507, James and Mike and Adrienne continue the discussion about our new clinical practice guideline on pain. We discuss the evidence for the treatments used for back pain and neuropathic pain and give you all the numbers and the nuances.

 Show Notes

1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
2. PEER pain calculator