TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

The BS Medicine Podcast episodes are presented by James McCormack and Michael Allan. We try to promote healthy skepticism and critical thinking and most of the podcasts are presented in a case-based approach. We also try to inject some humour into the whole process to make the learning more interesting. Occasionally we have great guests like Mike Kolber, Tina Korownyk and Bruce Arroll help us out.

Most podcast episodes are available for free until they become archived after about 1-2 months. Every 4th episode or so is a “New Studies You Need to Know About” podcast and these will only be available to our Premium Podcast members. Premium members will also be able to listen to all archived episodes since episode #1.

Episode 506: Removing the pain from dealing with chronic pain

In episode 506, James and Mike invite Adrienne Lindblad to discuss our latest clinical practice guideline on the management of chronic low back, osteoarthritic, and neuropathic pain in primary care. In this episode we describe the development process and then highlight the best available evidence, including both benefits and harms, for chronic osteoarthritis treatments. We talk about the other chronic pain topics in episode 507 so keep listening.

Show Notes

  1. PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care
  2. PEER pain calculator


Episode 505: NephMadness 2022 – albuminuria, basketball and the Great White North

In episode 505, James and Mike invite nephrologists Samira Farouk and Matthew Sparks to discuss the tricky issue of albuminuria – who to monitor, what to monitor and who to treat. We spend a lot of time dribbling and end up deciding that nothing is a slam dunk, so stay until the end for a real buzzer beater.

Show Notes

1) ACR variability

AJKD 2013;62:1095–1101

2) Kidney Failure Risk Equation

3) Albumin Handout

4) American Journal of Kidney Disease Blog

5) NephMadness 

6) May 27/28. 2022 The MEME conference – Making Evidence Matter For Everyone

Episode 504: Can It Stay or Must It Go? Extended Use of Intrauterine Devices

In episode 504, James and Mike invite Jen Potter back to the podcast to talk about whether or not intrauterine devices for preventing pregnancy can be used beyond the recommended duration of use. It seems one can defer IUD replacement for at least up to 12 months. Have a listen and see what you think.

Show Notes

1) Tools for Practice
Can It Stay or Must It Go? Extended Use of Intrauterine Devices

2) The Aural Apothecary Podcast – check it out

3) The MEME Conference – Make Evidence Matter for Everyone

4) CFPC Learn – Continuing Professional Development made by and for family physicians

Episode 503: Water, water everywhere – H-2-woah

In episode 503, James and Mike explore the evidence around water for a variety of different health outcomes. How much do we need and does it matter where we get it from? The only thing we know is that 8 glasses a day is wrong.

Show Notes

Coming soon

Episode 502: CO-KID – vaccine for kids

In episode 502, James, Mike Kolber and Tony Nickonchuk get together to talk about the easy question (just kidding) of COVID vaccines for children and adolescents. We discuss the best evidence we could find around efficacy and adverse effects in these age groups and hopefully give enough context so that you go from murky to somewhat less cloudy as to what we know and don’t know about this topic.

Show Notes

1) Tools for Practice
CO-KID: Covid vaccine for kids

2) Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents
January 12, 2022 DOI: 10.1056/NEJMoa2117995

3) Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12–18 Years — United States, June–September 2021

4) Effectiveness of BNT162b2 (Pfizer-BioNTech) mRNA Vaccination Against Multisystem Inflammatory Syndrome in Children Among Persons Aged 12–18 Years — United States, July–December 2021

Episode 501: PREMIUM – Kangaroos, Vitamin D guidelines and delayed antibiotics

In episode 501, Mike and James get back to being PREMIUM by talking about the impressive effect of Kangaroo care – listen to find out what that is. We also talk about the problem with guidelines around Vitamin D and yet again more evidence for delayed antibiotics.

Show Notes

1) Kangaroo mother care to reduce morbidity and mortality in low birthweight infants
Cochrane Database Syst Rev 2016 Aug 23;2016(8):CD002771
2) Immediate “Kangaroo Mother Care” and Survival of Infants with Low Birth Weight
N Engl J Med 2021;384:2028-38
3) Vitamin D recommendations in clinical guidelines: A systematic review, quality evaluation and analysis of potential predictors
Int J Clin Pract. 2021 Nov;75(11):e14805. doi: 10.1111/ijcp.14805. Epub 2021 Sep 15
4) Delayed Antibiotic Prescription for Children With Respiratory Infections: A Randomized Trial
Pediatrics. 2021 Mar;147(3):e20201323. doi: 10.1542/peds.2020-1323. Epub 2021 Feb 11.
5) Delayed antibiotic prescribing for respiratory tract infections: individual patient data meta-analysis
BMJ 2021;373:n808


James and Mike celebrate their 500th, YIKES, podcast episode. You get to hear the entire intro song (Some People) written and recorded by Pete McCormack. We talk about the history of the podcast, thank a lot of people, and talk about the key messages and the philosophy we have tried to impart over the years. We then discuss a few cases that bring all these ideas into focus. THANKS SO MUCH FOR LISTENING and going on this journey with us. We have had a blast.

Show Notes

Pete McCormack’s Website
Tools for Practice
PEER Evidence

Episode 499: No Gain, No Pain? – Diet-induced weight loss for OA knee pain

In episode 499, James and Mike invite Tina back again to discuss the evidence we have for dieting to lose weight and the impact of that on osteoarthritis knee pain. Overall, there isn’t a lot of evidence but some observational data suggests a benefit Unfortunately the relatively small weight loss achieved from most diets in RCTs did not demonstrate a difference on OA pain.

Show Notes

Tools for Practice
No Gain, No Pain? – What is the effect of diet-induced weight loss on osteoarthritis-related knee pain?

Episode 497: The Nutrition Proposition – a teaser

In episode 497, James and Mike decide to go all in on the evidence around nutrition. We start out by going over how we try to actually figure out if a food is beneficial or harmful for you. And for nutrition is it ever tricky.

Show Notes

The Nutrition Proposition – Coming Soon – I hope

See List of All Podcast Episodes


BS Medicine Podcast

MEME 2023 Conference May 12-13, 2023

Making Evidence Matter For Everyone | May 12 & 13, 2023
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice




Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.


BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

PEER Tools


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