In episode 552, James and Mike go over a couple of new trials. We talk about a blood pressure trial that examined taking the pills in the morning vs the evening and a heart failure trial that looked at getting patients on “high intensity” treatment.
Find out the results here.

Show notes

Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial
Lancet 2022 Oct 22;400(10361):1417-1425

Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial

Lancet 2022 Dec 3;400(10367):1938-1952

In episode 551, James and Mike invite Danielle Perry back to the podcast to talk about the best available evidence for the use of statins in people 65 and over. As you’ll hear, we have lots of evidence so all you need to know is what it says. Then, you can have an evidence-based discussion with all your people in this age category. After that discussion, your patient can make a decision one way or another and that means both of you win and you don’t have to care what guidelines say about this topic. Check it out.

Show notes

Tools for Practice
Statins in Older Adults

CFPC Learn

PEIP conference Oct 20-21 2023

In episode 550, James and Mike talk in a PREMIUM way about a new cholesterol lowering agent. Bempedoic acid is nothing tremendously exciting but what was very interesting was a subsequent publication that looked at a primary subset analysis, yet completely left out the secondary subset data. Have a listen and find out why.

Show Notes

Sensible Medicine
Lipid lowering – a Bempedoic Acid Subset Analysis – To be right, you have to also look at what is left

MyStudies

CFPC Learn

PEIP conference Oct 20-21, 2023

In episode 549, James and Mike invite Blair MacDonald to the podcast for the first time and we talk about a topic that we haven’t really covered to-date. We discuss the evidence around what happens to the risk of pancreatitis when we use triglyceride-lowering medications (fibrates, statins, niacin, omega-3s) in patients with hypertriglyceridemia. Have a listen as the results may surprise you somewhat.

Show Notes

Tools for Practice

Triglyce-Ride that High?

CFPC Learn

PEIP conference Oct 20-21 2023

In episode 548, James and Mike invite Betsy Thomas back to the podcast to talk about whether or not measuring lipoprotein(a) or apolipoprotein B improves cardiovascular risk prediction in a meaningful way over and above using standard risk factors. Many guidelines are now recommending we should do these measurements but is this an evidence-based recommendation? Give us 30 minutes of your time and you’ll know the answer.

Show Notes

Less is More Unless it’s Sleep or Toilet Paper: Non-traditional lipoproteins for cardiovascular risk
Tools for Practice

CFPC Learn

PEIP conference Oct 20-21 2023

In episode 547, James and Mike invite Jessica and Scott back again to talk about whether or not COPD patients seen in primary care are like the people studied in the large COPD trials. We talk about how to focus care on the people who are most likely to benefit from therapy. There are lots of important primary care tips in this one. Have a listen.

Show Notes

Risk and distribution of chronic obstructive pulmonary disease–related hospitalizations among primary care patients
Canadian Family Physician June 2023, 69 (6) 409-414

CFPC Learn
PEIP conference Oct 20-21 2023

Episode 546: Who provides chronic disease management?

In episode 546, James and Mike invite Jessica Kirkwood and Scott Garrison to talk about a new study they published looking at what proportion of common chronic medical conditions such as hypertension, diabetes and COPD are handled by family physicians, specialists, and nurse practitioners manage. We find that family physicians provide the majority of care for these conditions. Tune in to find out the actual numbers and possibly how these findings should be used.

Show Notes

Who provides chronic disease management?
Canadian Family Physician June 2023, 69 (6) e127-e133 

CFPC Learn

PEIP conference Oct 20-21 2023

In episode 545, James and Mike invite Samantha Moe back again to the podcast to talk about whether or not statins increase the risk of dementia or worsening of cognitive scores. I forgot the answer so you will have to listen to the podcast.

Show Notes
Tools for Practice
Forget about it? Statins and the risk of dementia

CFPC Learn

PEIP conference Oct 20-21 2023

In episode 544, James and Mike invite Samantha Moe to the podcast to talk about whether or not PPIs improve crying, fussiness, irritability, or regurgitation attributed to feeds. If you’ve ever used PPIs for this condition, you may be surprised by the results.

Show Notes
1) Tools for Practice
Crying babies: Can proton pump inhibitors help?
2) CFPC Learn
3) PEIP conference Oct 20-21 2023

In episode 543, James and Mike invite Tina Korowynk and Jennifer Young to discuss their recent paper where they talk about the evidence around comprehensive primary care that is led by a family physician. We find out family physician care improves patient outcomes such as mortality, decreased emergency department visits, hospitalizations, readmissions, and health care costs. At the end we discuss a few ideas for how to start to solve some of the issues that have created the present primary care crisis.

Show Notes
The value of family medicine: An impossible job, done impossibly well
Canadian Family Physician 2023;69:269-270