In episode 269, the Mikes and James go viral on the HPV vaccine. We discuss what the evidence shows around the use of the HPV vaccine in females and males and in contrast to many people, we actually present the numbers so that you can help people, or help yourself make decisions.
Show notes
1) Tools for Practice
In episode 268, Mike and James discuss the use of benzodiazepines in the management of agitation in demented elders. We discuss the evidence and realise that the evidence is at best iffy. Nonetheless, they seem to be as effective as antipsychotics but both classes of drugs have side effects and should be used in low doses and stopped as soon as possible.
Show notes
1) Tools for Practice
In episode 267, James and Mike finally get to the first PREMIUM podcast of 2015 – and boy is it something. We discuss a new paper put out by the Edmonton gang on who actually contributes to primary care guidelines, we talk about a new systematic review of mild hypertension treatment, and finally discuss a NEJM article on the duration of dual antiplatelets. At the end we both agree this podcast was really something.
Show notes
1) Contributors to primary care guidelines
Can Fam Physician 2015;61:52-8
2) Effects of Blood Pressure Reduction in Mild Hypertension
A Systematic Review and Meta-analysis
Ann Intern Med. 2015;162(3):184-191. doi:10.7326/M14-0773
3) Twelve or 30 Months of Dual Antiplatelet Therapy after Drug-Eluting Stents
In episode 266, James and Mike finally get to the end of listener questions. We talk about NSAIDs and inflammation, cognitive impairment and statins, dosing of antibiotics, antidepressants and efficacy, and antiplatelets and ethnicity. We give answers which either clarify or confuse the issues.
Show notes
1) Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis
2) Selective publication of antidepressant trials and its influence on apparent efficacy
3) Why olanzapine beats risperidone, risperidone beats quetiapine, and quetiapine beats olanzapine: an exploratory analysis of head-to-head comparison studies of second-generation antipsychotics
In episode 265, Mike and James continue with listener questions. We tackle issues around calories, alcohol intake, nutrition, diabetes and so much more. We provide answers and so much less.
Show notes
1) Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis
In episode 264, James and Mike continue trying to answer listener questions. We tackle issues around blood viscosity, nutrition, and diabetes medications with abandon, and hopefully provide some useful information.
Show notes
In episode 263, Mike and James finally get back to the whole podcasting thing and answer a bunch of great listener questions. We leave it to the listeners to decide if our answers are of a similar great calibre.
Show notes
1) Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department
In episode 262, Tina, Mike and James discuss the ins and outs of their new BMJ paper on televised medical talk shows. TMJ and the gang did a thorough investigation of the recommendations made by two nationally televised medical talk shows (The Dr Oz Show and The Doctors). We looked at what specifically these shows recommended and what was the evidence behind these recommendations – in other words how believable were their recommendations. Have a listen, go read the paper and you’ll be armed with the best available evidence around the recommendations made by these shows.
Show notes
The BMJ article
In episode 261, Mike and James finish examining the evidence surrounding the periodic health exam. We discuss the don’t do’s when it comes to test ordering and screening. At the end James congratulates Mike on the great job he did with this podcast trilogy and this shocks Mike so much he suggests James come in for an extensive periodic health exam.
Show notes
In episode 260, Mike and James continue examining the evidence surrounding the periodic health exam. We discuss the dos and maybe nots and the whats we should be doing around test ordering and screening. At the end we realise we probably do more than we really should and that is important for us and our patients to be aware of the benefits and harms of what we do.
Show Notes
THE NUTRITION PROPOSITION BOOK
Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.
