In episode 331, James and Mike talk about the ups and downs of erectile dysfunction. We take a penetrating look at the epidemiology and what initial assessments should be done – treatments will pop-up in the next podcast. Fortunately or unfortunately, we rarely raise our comments above what would be expected from 14 year-old boys.
Show notes
In episode 330, Mike and James do a PREMIUM job of looking at 2 important new publications about medications for type 2 diabetes. We look at an RCT of semaglutide that actually shows a benefit. We then look at a very thorough systematic review/meta-analysis of all the studies and publications around T2DM since 1998. The results demonstrate very clearly that the evidence doesn’t really support what is being written in the diabetes clinical practice guidelines.
Show notes
1) SUSTAIN-6
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
N Engl J Med 2016; 375:1834-44
2) Glycemic Control for Patients With Type 2 Diabetes Mellitus Our Evolving Faith in the Face of Evidence
Circ Cardiovasc Qual Outcomes. 2016;9:00-00. DOI: 10.1161/CIRCOUTCOMES.116.002901.
In episode 329, Mike and James continue with their update on the treatment of dementia. We talk about prevention and how to figure out if an individual is getting a benefit from treatment. Bottom line, it is very tricky. We also talk about non-drug treatments and the latest new drug treatment.
Show notes
See Episode 328
THE NUTRITION PROPOSITION BOOK
Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.
This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)
