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Episode 140: Polypharmacy – a pollyanna approach to a polymorphic problem

In episode 140, Mike and James do a lot of drugs in an attempt to bring a reality to the whole concept of polyharmacy. After recovering, we try to present a lucid and comprehensive approach to the issues of polypharmacy and come to the realisation that drugs can be good, bad and ugly all in the same person and you have to individualise to rationalise.

Show notes

1) Polypharmacy/polyproblem numbers

J Am Med Dir Assoc 2011 Aug 11

BMC Clinical Pharmacology 2010;10:16 

N Engl J Med 1994;331:821-7

Drugs Aging 2011;28:547-60

Drugs Aging 2009;26:1039-48

Am J Geriatr Pharmacother 2007;5:345-51

Ann Fam Med 2005;3:223-8

MJA 2008;189:72-7

2) Solutions?

Drugs Aging 2008;25:307-24

BMJ 2006;333:522

Isr Med Assoc J 2007;9:430-4

Lancet Neurology 2009;8:151-7

Arch Intern Med 2010;170:1648-54

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