TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 186: A spine-tingling look at neuropathic pain – PART II

In episode 186, Mike and James continue on the path of the treatment of neuropathic pain and we explore the whole murky world of gabapentin and pregabalin. We come to the conclusion that while these drugs produce an effect and also produce side effects it’s all about the overall magnitude of that effect. Go figure.

Show notes

1) Gabapentin

Cochrane review

CD007938

N Engl J Med 2009;361:1963-71 

Therapeutics Letter #75 – 2009 

2) Pregabalin

Cochrane review

CD007076

CDR Sept 23, 2009, pregabalin review 

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