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Episode 188: PREMIUM – Taking a bite out of fasting for cholesterol measurements and more bad news about low A1cs

 

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In episode 188, James and Mike go all PREMIUM for the holidays and discuss a few studies that have the potential to change practice. These include info on the impact or lack thereof of fasting on cholesterol measurements, the impact of A1c on functional decline and a head-to-head comparison of metformin and glipizide.

1) Variability in cholesterol measurement

JAMA 1992;267:1652-60

2) Effect of fasting on cholesterol measurements

Arch Intern Med 2012;172:1707-10

3) Impact of glycosylated hemoglobin on functional decline

J Am Geriatr Soc 2012;60:1215–21

4) SPREAD-DIMCAD

Diabetes Care 2012 Dec 10 (Epub ahead of print)

 

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The 2026 MEME Conference – May 8-9, 2026

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