TEC: Evidence Based Therapeutics
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Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 2: Evidence does not equal decision-making

In our second session we discuss the philosophy of calculating risk and the many factors that influence the application of these numbers. We each calculate risk using our personal preference for risk estimators and discuss the mystery of why these numbers are not the same. “Treating” asymptomatic patients and instituting preventive interventions taken for a life time does not require great haste.

Show Notes

Canadian Cardiovascular Society Risk Calculator

12 points =10% risk in 10 years (of non-fatal MI or coronary death)

Risk factors Points
Age 3
Total cholesterol 6
HDL 2
BP 1
Smoke 0
TOTAL 12

Can J Cardiol 2006;22(11):913-27

Our 45 y/o 10-year risk

Framingham
10 year chance of CVD
Overall CVD 14.1%
CHD 12.3%
MI 6.4%
Stroke 1.2%
Death of CVD 2.0%
Death for CHD 2.0%

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