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Episode 258: IMPROVE-IT – ezetimibe, what it does and doesn’t do

Episode 258: IMPROVE-IT – ezetimibe, what it does and doesn’t do 

In episode 258, James and Mike discuss the very recently released IMPROVE-IT study that was presented November 17th, 2014 at the AHA meeting. We discuss what was found and what wasn’t found and whether or not these results lend credence to the lipid hypothesis. We find that finally a drug used to change a surrogate marker actually appears to reduce cardiovascular events (we have had 20 negative trials in a row before this) but the magnitude is certainly not huge. We discuss the nuances of the results and hopefully put it into a reasonable perspective.

Show notes

1) A copy of the IMPROVE-IT slides from the AHA meeting  

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11th Annual PEIP Conference October 21-22, 2022

Practical Evidence for Informed Practice Conference | October 21 & 22, 2022
Led by the team that brings you Tools for Practice, the Practical Evidence for
Informed Practice (PEIP) Conference brings together clinical leaders to speak on
the latest findings that can affect how you practice.

www.peipconference.ca

BIG ANNOUNCEMENTS

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

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BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

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