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Episode 271: PREMIUM – DESCARTES, OSLER, ODYSSEY and what you need to know

In episode 271, James and Mike discuss the most recent evidence for two new monoclonal antibody medications that lower lipids. We discuss the two new studies OSLER and ODYSSEY. At the end we both agree that it is great these studies looked at cardiovascular events and at least they are going in the right direction. However, we still have a long way to go before we would consider using them.

Show notes

 Study synopses can be found at mystudies.org

DESCARTES

A 52-Week Placebo-Controlled Trial of Evolocumab in Hyperlipidemia

OSLER

Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events 

ODYSSEY LONG TERM

Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events

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