TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 83: Gabapentin and bioidentical hormones – a look at ALL the data

In episode 83, Mike and James tackle two very different and difficult areas of controversy. Mike looks at the data surrounding the use of gabapentin and off-label uses including chronic pain, and James tackles the lack of data surrounding the use of bioidentical hormones. At the end of the podcast James develops breast tenderness and complains so much that Mike decides to take gabapentin for the pain associated with James’ complaining.

Show notes

1) Off-label trials of gabapentin

N Engl J Med 2009;361:1963-71

2) CIHR trials

CMAJ 2004;171:735-40

3) Gabapentin for pain

Therapeutics Initiative Letter 2009 (July – Dec)

4) Pregabalin

First CEDAC report

Final recommendation

5) Systematic review of bioidentical hormones

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