TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

The BS Medicine Podcast episodes are presented by James McCormack and Michael Allan. We try to promote healthy skepticism and critical thinking and most of the podcasts are presented in a case-based approach. We also try to inject some humour into the whole process to make the learning more interesting. Occasionally we have great guests like Mike Kolber, Tina Korownyk and Bruce Arroll help us out.

Most podcast episodes are available for free until they become archived after about 1-2 months. Every 4th episode or so is a “New Studies You Need to Know About” podcast and these will only be available to our Premium Podcast members. Premium members will also be able to listen to all archived episodes since episode #1.

Episode 377: Getting higher than a kite with medical cannabinoid evidence – PART IV

In episode 377, Mike and James finally get to the end of looking at all the available cannabinoid evidence and we continue to discuss how the evidence could be used in the context of a shared-decision making process.

Show notes

Simplified guideline for prescribing medical cannabinoids in primary care 

Canadian Family Physician 2018;64:111-20

Cannabinoid short summary

Cannabinoid patient summary

Episode 376: Getting higher than a kite with medical cannabinoid evidence – PART III

In episode 376, Mike and James take all the best available evidence around cannabinoid use and put the evidence into the concept of a shared-decision making guideline. Shocking as it may seem, shared-decision making is rarely a part of most guidelines but we show how valuable it can be to keep this concept in focus when it comes to giving suggestions for the use of many treatments.

Show notes

Simplified guideline for prescribing medical cannabinoids in primary care 

Canadian Family Physician 2018;64:111-20

Cannabinoid short summary

Cannabinoid patient summary

Episode 375: Getting higher than a kite with medical cannabinoid evidence – PART II

In episode 375, Mike and James continue getting high on the evidence around medical cannabinoids. We talk about the adverse effects associated with medical cannabinoids and find out it is fairly impressive in not only the number of patients who get them but also the different kinds of side effects.

Show notes

Systematic review of systematic reviews for medical cannabinoids

Canadian Family Physician February 2018;64:e78-e94

Episode 374: Getting higher than a kite with medical cannabinoid evidence

In episode 374, Mike and James get high by delving into a systematic review of medical cannabinoids. We put a flame to the evidence, munch on all the data and get the giggles around what the evidence actually shows. The bottom line is, there is evidence for its use in pain, nausea and vomiting, and spasticity but the evidence is at best stoned.

Show notes

Systematic review of systematic reviews for medical cannabinoids

Canadian Family Physician February 2018;64:e78-e94

Episode 373: Back to listener questions – finally – PART III

In episode 373, Mike and James get back to the last of the listener questions. We talk about vaginal infections, statins (of course), diabetes, medical education, alcohol hand sanitizers and TPA yet again. As always, we leave everyone with more questions than before we started – you have to love healthcare.

Episode 371: Back to listener questions – finally

In episode 371, James and Mike get back to listener question. We talk about iron, TPA, big blood pressure numbers, antipsychotics and lab measurements. Hopefully we leave the audience with more answers than questions.

Show notes

1) Are we giving too much iron? Low-dose iron therapy is effective in octogenarians

Am J Med 2005;118:1142-7

2) Clot – dissolving drugs for treating ischaemic stroke in the early stages

Cochrane Review

3) Effect of Propranolol In Mild Hypertension

Lancet 1966;288:1148–50

4) Head-to-head comparisons of metabolic side effects of second-generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis

Schizophr Res 2010;123:225-33

5) Chronic Kidney Disease (CKD) Clinical Pathway

Episode 370: PREMIUM – Back pain, knee pain, fractures and skin abscesses

In episode 370, Mike and James decide to follow their New Year’s resolution by trying to present some new studies in a useful and thoughtful way – in other words, a PREMIUM podcast. We talk about a trial of pregabalin for sciata, a trial of intra-articular steroid injections for knee pain, romosozumab/alendronate for fractures and antibiotics for small abscesses.

Show notes

1) Trial of Pregabalin for Acute and Chronic Sciatica

N Engl J Med 2017;376:1111-20

2) Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial

JAMA 2017;317:1967-75

3) Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis

N Engl J Med 2017; 377:1417-27

4) A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses

N Engl J Med 2017;376:2545-55

Episode 369: Early Peanuts for Little Peanuts: The not so paltry benefits

In episode 369, James and Mike ask Tina back again to talk about the tricky and tasty issue of peanut allergies. We talk about the landmark study in this area and then put it into context of all the other evidence we have around this issue. We then discuss what we should likely be recommending when it comes to peanut ingestion in early childhood.

Show notes

1) Tools For Practice

Early Peanuts for Little Peanuts: The not so paltry benefits

2) Instructions for home feeding of peanut protein

See List of All Podcast Episodes

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The 2026 MEME Conference – May 8-9, 2026

REGISTRATION IN JANUARY 2026

Making Evidence Matter For Everyone | May 8-9, 2026
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice

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BIG ANNOUNCEMENT

THE NUTRITION PROPOSITION BOOK

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

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