TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 136: PREMIUM – A head-to-head comparison of ezetimibe and prunes

In episode 136, James and Mike once again raise the content bar level with the premium of all PREMIUM podcasts. We talk about a study that looked at the effect of ezetimibe plus simvastatin and we get a very clear answer but unfortunately the question that was asked was completely wrong. We then bring the podcast to a rising never ending crescendo by discussing a “pivotal” trial comparing psyllium to prunes in chronic constipation and low and behold the answer is extremely useful and relevant to day-to-day practice. 

Shownotes

1) SHARP TRIAL

Lancet 2011;377:2181-92

2) The PRUNE trial

Aliment Pharmacol Ther 2011;33:822–8

3) An Evidence-Based Approach to the Management of Chronic Constipation in North America

Am J Gastroenterol 2005;100 Suppl 1:S5-S21

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11th Annual PEIP Conference October 21-22, 2022

Practical Evidence for Informed Practice Conference | October 21 & 22, 2022
Led by the team that brings you Tools for Practice, the Practical Evidence for
Informed Practice (PEIP) Conference brings together clinical leaders to speak on
the latest findings that can affect how you practice.

www.peipconference.ca

BIG ANNOUNCEMENTS

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

BS Medicine Podcast

BedMed: The High Blood Pressure Study

This pragmatic trial is now recruiting in BC. Make a difference and get involved with pragmatic trials (www.pragmatictrials.ca)

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