TEC: Evidence Based Therapeutics
Therapeutics Education Collaboration
Medication Mythbusters – Home of the Best Science (BS) Medicine Podcast

Episode 136: PREMIUM – A head-to-head comparison of ezetimibe and prunes

In episode 136, James and Mike once again raise the content bar level with the premium of all PREMIUM podcasts. We talk about a study that looked at the effect of ezetimibe plus simvastatin and we get a very clear answer but unfortunately the question that was asked was completely wrong. We then bring the podcast to a rising never ending crescendo by discussing a “pivotal” trial comparing psyllium to prunes in chronic constipation and low and behold the answer is extremely useful and relevant to day-to-day practice. 

Shownotes

1) SHARP TRIAL

Lancet 2011;377:2181-92

2) The PRUNE trial

Aliment Pharmacol Ther 2011;33:822–8

3) An Evidence-Based Approach to the Management of Chronic Constipation in North America

Am J Gastroenterol 2005;100 Suppl 1:S5-S21

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MEME 2023 Conference May 12-13, 2023

Making Evidence Matter For Everyone | May 12 & 13, 2023
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice

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BIG ANNOUNCEMENT

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

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