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Episode 61: Type 2 Diabetes – how sweet it isn’t – Part VII

In the 61st episode, the seventh podcast in our thesis on type-2 diabetes, we get off the topic of glucose and talk about STENO and blood pressure treatments. We decide the bottom line is control of blood pressure with low doses of thiazides and ACE inhibitors with no tolerance for side effects. Mike’s blood pressure goes up with some of James’ suggestions but high doses of reserpine, methyldopa and clonidine calm him down.

Show Notes

1) STENO

N Engl J Med 2008;358:580-91

2) Blood pressure trials UKPDS 38

BMJ 1998;317:703-13

HOT Trial

Lancet 1998;351:1755-62

Do ACEI/ARBs uniquely protect the kidney – No?

Lancet 2005;366:2026-33

ALLHAT

JAMA 2002;288:2981-97

Low doses of ACEI – most of the BP effect is from low doses

Cochrane Library

MICROHOPE

Lancet 2000;355:253-59

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MEME 2023 Conference May 12-13, 2023

Making Evidence Matter For Everyone | May 12 & 13, 2023
From the clinicians who brought you the Best Science Medicine Course and the Meds Conference, as well as the BS Medicine Podcast and Tools for Practice

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BIG ANNOUNCEMENT

THE NUTRITION PROPOSITION BOOK HAS JUST BEEN RELEASED

Check it out at nutritionproposition.com and think about picking up a copy on Amazon. All the evidence you ever wanted about nutrition and the only nutrition book that won’t tell you what to eat.

 

BedMed: The High Blood Pressure Study

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